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Strategies for Understanding and Reducing the and Hypnozoite Reservoir in Papua New Guinean Children: A Randomised Placebo-Controlled Trial and Mathematical Model


Ivo Mueller and colleagues conduct a randomized controlled trial of blood-only or blood- plus liver-stage malaria drugs to identify the contribution of relapses to the burden of P. vivax and P. ovale in children in Papua New Guinea, and model the potential impact of mass-drug administration to prevent recurrent P. vivax infections.


Vyšlo v časopise: Strategies for Understanding and Reducing the and Hypnozoite Reservoir in Papua New Guinean Children: A Randomised Placebo-Controlled Trial and Mathematical Model. PLoS Med 12(10): e32767. doi:10.1371/journal.pmed.1001891
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pmed.1001891

Souhrn

Ivo Mueller and colleagues conduct a randomized controlled trial of blood-only or blood- plus liver-stage malaria drugs to identify the contribution of relapses to the burden of P. vivax and P. ovale in children in Papua New Guinea, and model the potential impact of mass-drug administration to prevent recurrent P. vivax infections.


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