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Tempo and Mode of Transposable Element Activity in Drosophila


Transposable elements (TE) are stretches of DNA that propagate autonomously within genomes, but it is not clear whether TEs are moving at a constant rate or if TE activity is variable. Determining the genome-wide TE content of two closely related Drosophila species, we show that transposition rate heterogeneity is abundant. Since TE insertions are frequently associated with a selective advantage, we suggest that the observed high TE activity may have served a central role facilitating the adaptation of the two species to their novel environments after the recent out of Africa habitat expansion.


Vyšlo v časopise: Tempo and Mode of Transposable Element Activity in Drosophila. PLoS Genet 11(7): e32767. doi:10.1371/journal.pgen.1005406
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1005406

Souhrn

Transposable elements (TE) are stretches of DNA that propagate autonomously within genomes, but it is not clear whether TEs are moving at a constant rate or if TE activity is variable. Determining the genome-wide TE content of two closely related Drosophila species, we show that transposition rate heterogeneity is abundant. Since TE insertions are frequently associated with a selective advantage, we suggest that the observed high TE activity may have served a central role facilitating the adaptation of the two species to their novel environments after the recent out of Africa habitat expansion.


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