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Treatment of subglottic stenosis: results and factors influencing treatment success


Authors: Monika Debnárová 1 ;  Pavel Komínek 1,2 ;  Karol Zeleník 1,2
Authors‘ workplace: Klinika otorinolaryngologie a chirurgie hlavy a krku, FN Ostrava 1;  Katedra kraniofaciálních oborů, Lékařská fakulta OU, Ostrava 2
Published in: Otorinolaryngol Foniatr, 74, 2025, No. 3, pp. 189-194.
Category: Original Article
doi: https://doi.org/10.48095/ccorl2025189

Overview

Introduction: Subglottic stenosis is a narrowing of the airways, starting below the vocal cords and extending to the lower edge of the cricoid cartilage. It can be a serious or life-threatening condition, with a risk of suffocation. Tracheostomy is often necessary with all the negative consequences that result from it. The most common cause of subglottic stenosis is previous intubation or tracheotomy. The aim of the present study was to evaluate the success of surgical treatment of patients with subglottic stenosis and to identify the risk factors affecting the success of treatment. Materials and methods: Retrospective analysis of patients with diagnosed symptomatic subglottic stenosis who underwent surgical treatment at the Department of Otorhinolaryngology and Head and Neck Surgery of the Ostrava University Hospital in 2013–2022. Data were obtained from the hospital information system and then were statistically processed. Treatment was considered successful if it allowed the patient to decannulate or if breathing improved. Results: Out of the total number of 65 patients, treatment was successful in 54/65 (83%). Out of the 30 patients with a tracheotomy cannula, 20/30 patients (67%) could be decannulated. Of all the monitored parameters, only a higher BMI had a statistically significant negative impact on the outcome of treatment (P = 0.003). Success of treatment was not significantly affected by the type and severity of stenosis, the presence of tracheomalacia, Covid-19 infection, or the selected therapy. Conclusion: Surgical treatment of subglottic stenosis was successful in 83% of the patients. Obesity is a negative prognostic factor in terms of treatment success.

Keywords:

obesity – endoscopic treatment – treatment outcomes – tracheal resection – subglottic stenosis – cricotracheal resection


Sources

1. Jagpal N, Sommerfeldt J, Shabbir N. Subglottic Stenosis. Treasure Island (FL): StatPearls Publishing 2023. In: StatPearls. 2023 [online]. Dostupné z URL: https: //www.ncbi.nlm.nih.gov/books/NBK563265/.

2. Almanzar A, Danckers M. Laryngotracheal Stenosis. Treasure Island (FL): StatPearls Publishing 2023. In: StatPearls. 2023 [online]. Dostupné z URL: https: //www.ncbi.nlm.nih.gov/books/NBK554561/.

3. Zeleník K, Komínek P, Zábrodský M et al. Příručka pro praxi: Stenózy hrtanu a průdušnice. 2020 [on-line]. Dostupné z URL: https: //www.otorinolaryngologie.cz/content/uploads/2020/ 02/ppp-stenozy-hrtan.pdf.

4. Zias N, Chroneou A, Tabba MK et al. Post tracheostomy and post intubation tracheal stenosis: report of 31 cases and review of the literature. BMC Pulm Med 2008; 18 (8). Doi: 10.1186/1471-2466-8-18.

5. Miwa M, Nakajima M, Kaszynski R et al. Two cases of post-intubation laryngotracheal stenosis occurring after severe COVID-19. Intern Med 2021; 60 (3): 473–477. Doi: 10.2169/inter -⁠ nalmedicine.6105-20.

6. Bibas BJ, Cardoso PFG, Minamoto H et al. Quality-of-life evaluation in patients with laryngotracheal diseases. Transl cancer Res 2020; 9 (3): 2099–2101. Doi: 10.21037/tcr.2020.02.60.

7. Rosow DE, Barbarite E. Review of adult laryngotracheal stenosis: pathogenesis, management, and outcomes. Curr Opin Otolaryngol Head Neck Surg 2016; 24 (6): 489–493. Doi: 10.1097/MOO.0000000000000305.

8. Lukáš J, Paska J, Votruba J et al. Postkanylační stenózy trachey. Otorinolaryngol Foniatr 2007; 56 (3): 133–136.

9. Chrbolka P. Zúžení průdušnice, diagnostika a možné způsoby řešení. Prakt Lék 2010; 90 (2): 106–109.

10. Bah MD, Diop/Ndoye M, Outsouta Gn et al. Post-Intubation Tracheal Stenosis: Multicenter Study from 2010 to 2022. EAS J Anesthesiol Crit Care 2023; 5 (4): 63–69. Doi: 10.36349/easjacc.2023.v05i04.002

11. Feinstein AJ, Goel A, Raghavan G et al. Endoscopic Management of Subglottic Stenosis. JAMA Otolaryngol Head Neck Surg 2017; 143 (5): 500–505. Doi: 10.1001/jamaoto.2016.4131.

12. Melkane AE, Matar NE, Haddad AC et al. Management of postintubation tracheal stenosis: appropriate indications make outcome differences. Respiration 2010; 79 (5): 395–401. Doi: 10.1159/000279225.

13. Karvandian K, Jafarzadeh A, Hajipour A et al. Subglottic stenosis following percutaneous tracheostomy: a single centre report as a descriptive study. Acta Otorhinolaryngol Ital 2011; 31 (4): 239–242.

14. Li M, Yiu Y, Merrill T et al. Risk factors for posttracheostomy tracheal stenosis. Otolaryngol Head Neck Surg 2018; 159 (4): 698–704. Doi: 10.1177/0194599818794456.

15. Arellano-Rodríguez I, Machado J, Canché-Martín E et al. Laryngotracheal stenosis: Experience of a hospital in Northwestern Mexico. Rom J Rhinol 2022; 12 (45): 43–48. Doi: 10.2478/rjr-2022-0007.

16. Karmali S, Rose P. Tracheal tube size in adults undergoing elective surgery –⁠ a narrative review. Anaesthesia 2020; 75 (11): 1529–1539. doi: 10.1111/anae.15041.

17. Songu M, Ozkul Y. Risk factors for decannulation failure after single-stage reconstruction of adult post-intubation tracheal stenosis: 10-year experience at a tertiary center. Acta Otolaryngol 2020; 140 (4): 333–336. Doi: 10.1080/00016489.2020.1716071.

18. Halum SL, Ting JY, Plowman EK et al. A multi-institutional analysis of tracheotomy complications. Laryngoscope 2012; 122 (1): 38–45. Doi: 10.1002/lary.22364.

19. Nicolli EA, Carey RM, Farquhar D et al. Risk factors for adult acquired subglottic stenosis. J Laryngol Otol 2017; 131 (3): 264–267. Doi: 10.1017/S0022215116009798.

20. Pappal RB, Burruss CP, Witt MA et al. Risk factors for developing subglottic and tracheal stenosis from the medical intensive care unit. Laryngoscope Investig Otolaryngol 2023; 8 (3): 699–707. Doi: 10.1002/lio2.1051.

21. Snow GE, Shaver TB, Teplitzky TB et al. Predictors of Tracheostomy Decannulation in Adult Laryngotracheal Stenosis. Otolaryngol Head Neck Surg 2021; 164 (6): 1265–1271. Doi: 10.1177/0194599820978276.

22. Hseu AF, Benninger MS, Haffey TM et al. Subglottic stenosis: a ten-year review of treatment outcomes. Laryngoscope 2014; 124 (3): 736–741. Doi: 10.1002/lary.24410.

23. Lavrysen E, Hens G, Delaere P et al. Endoscopic Treatment of Idiopathic Subglottic Stenosis: A Systematic Review Front Surg 2020; 75 (6). Doi: 10.3389/fsurg.2019.00075.

24. Mandour M, Remacle M, Van de Heyning P et al. Chronic subglottic and tracheal stenosis: endoscopic management vs surgical reconstruction. Eur Arch Otorhinolaryngol 2003; 260 (7): 374–380. Doi: 10.1007/s00405-002 -⁠ 0578-3.

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Audiology Paediatric ENT ENT (Otorhinolaryngology)
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