Non-melanocytic Dischromias

České info

Nemelaninové dyschromie

Mimo melaninových existují i nemelaninové pigmentace, kdy se pigment různého původu, vznikající endogenně nebo přicházející ze zevního prostředí, ukládá do kůže a dlouhodobě ji zbarvuje. Exogenně vznikající hyperpigmentace se vyvíjejí vesměs po lécích, endogenně podmíněné pak při různých metabolických poruchách. Všechny hyperpigmentace provází různě vyjádřená fotosenzibilita někdy toxického, jindy alergického charakteru. Kromě vyhýbání se lékům a chemikáliím se známou pigmentační schopností spočívá terapie vesměs jen v důsledné fotoprotekci.

Klíčová slova:
pigmentace, hyperpigmentace, fototoxicita, fotoalergie, fotoprotekce.

Authors: L. Malina
Authors‘ workplace: Katedra dermatovenerologie IPVZ, Praha
Published in: Čas. Lék. čes. 2005; 144: 805-807
Category: Review Article

Overview

Non-melanocytic hyperpigmentations (dyschromias), besides common melanotic ones, develop mostly due to the skin reaction to various chemicals and/or drugs of exogenous origin. They can be however also caused by some endogenously formed (evolving) intermediates of several metabolic diseases. The above mentioned factors are of toxic or allergic character and their clinical dermal manifestation often occurs as an allergic reaction after the exposition of the skin to solar radiation, or as a toxic contact reaction both on the skin and the mucosa. As a therapy of individual skin changes is difficult or impossible, the only treatment consists in reliable photoprotective measures.

Key words:
pigmentation, hyperpigmentation, phototoxicity, photoallergy, photoprotection.

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Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental Hygienist

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