Combined Immunosuppressive Therapy in Patients with Pemphigus Vulgaris and Its Side Effects

České info

Kombinovaná imunosupresivní terapie u pacienta s pemfigus vulgaris a vedlejší účinky léčby

Pemfigus vulgaris je autoimunitní puchýřnaté onemocnění kůže a sliznic, neléčené s vysokou mortalitou, při terapii kortikosteroidy a imunosupresivy se závažnými vedlejšími účinky. Kazuistika popisuje případ pacienta s histologicky verifikovanou diagnózou pemfigus vulgaris, u něhož se stabilizace onemocnění dosáhlo obtížně a již záhy se rozvinuly vedlejší účinky kombinované imunosupresivní terapie.

Klíčová slova:
pemfigus vulgaris, imunosupresivní terapie, nežádoucí účinky léčby.

Authors: N. Vojáčková; I. Hejcmanová; R. Schmiedbergerová; J. Hercogová
Authors‘ workplace: Dermatovenerologická klinika 2. LF UK a FN Na Bulovce, Praha
Published in: Čas. Lék. čes. 2005; 144: 833-835
Category: Case Report

Overview

Pemhigus vulgaris is an autoimmune bullous disease of the integument. When not treated, it has a high mortality, the treatment with corticosteroids and immunosuppressives has serious side effects. Our casuistry gives a case of patients with histologically verified diagnosis of pemphigus vulgaris. In this case the stabilization of the disease was difficult and side effects of the combined immunosuppressive therapy developed very early.

Key words:
pemhigus vulgaris, immunosuppressive therapy, undesired side effects.

Labels

Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental Hygienist

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