COVID-19 from the view of free radicals and antioxidants
COVID-19 z hlediska volných radikálů a antioxidantů
COVID-19 poškozuje buňky a tkáně oxidačním stresem, ale to v současné době není dost známo. Ochrana před volnými radikály by mohla zlepšit stav nemocných a snížit jejich počet. Některé antioxidanty a postupy jsou slibné a zaslouží si publikaci. Terapie COVID-19 infekce z hlediska oxidoredukčních stavů by měla probíhat následujícími fázemi: 1. Zabránit množení viru a oxidačnímu stresu (antioxidant flavonoid taxifolin?). Terapie antioxidanty má smysl jen tehdy, jde-li o převahu volných radikálů. Jinak by byla kontraproduktivní; 2. Bránit mutacím (selen a snad antioxidanty, protože volné radikály umí mutovat nukleové kyseliny. Koronarovir je monovláknová RNA). Tím by se mohlo zabránit vzniku mutované formy viru, na kterou ještě člověk nemá protilátky = zábrana druhé vlny infekce); 3. Zabít viry (pokud ještě zůstaly virulentní v těle a tak bránit se proti latentní infekci a opakování onemocnění, (UVB paprsky, viruscidní látky, kombinace antioxidantů, očkování, atd.).
Klíčová slova:
COVID-19 – oxidační stres – antioxidanty – volné radikály
Authors:
V. Holeček
Authors‘ workplace:
OKB, Mulačova nemocnice, Plzeň
Published in:
Klin. Biochem. Metab., 29, 2021, No. 2, p. 60-63
doi:
https://doi.org/10.61568/kbm.2021.009
Overview
Covid-19 damages cells and tissues by oxidative stress, but currently is not known enough. Protection from free radicals could improve the condition of patients and decrease the number of sicks. Some antioxidants and methods are promising and deserve publication. Therapy of COVID-19 infection termed oxidoreduction states should take place in the following phases: 1. Prevent the virus from multiplying and from oxidative stress (antioxidant flavonoid taxifolin?). Antioxidative therapy only makes sense when it comes about dominance of free radicals. Otherwise, it would be counterproductive; 2. Prevent mutations (selenium and probably antioxidants, because free radicals can mutate nucleic acids. Coronavirus is single-branched RNA). This could prevent the emergence of mutated form of virus, to which human does not yet have antibodies - prevention of second wave of infection); 3. Kill viruses (if they remained virulent in the body and so defend against latent infection and repetition of disease (UVB rays, virucidal substances, combination of antioxidants, vaccination, etc.).
Keywords:
Antioxidants – oxidative stress – Free radicals – COVID-19
Labels
Clinical biochemistry Nuclear medicine Nutritive therapistArticle was published in
Clinical Biochemistry and Metabolism
2021 Issue 2
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