DESIGN CONCEPTS FOR PREVENTING GAS BUBBLE INTERFERENCE IN MICROFLUIDIC DEVICES


Unintendedly introduced gas bubbles in channels can significantly interfere with performance and behavior of microfluidic systems. Thus, there is a high demand for smart microfluidic system designs which are capable of preventing gas bubbles. In this work, we develop two different bubble interference preventing system designs: a degasser device that actively removes gas bubbles from the liquid based on pressure driven gas permeation, and a passive micro channel design that provides a guiding mechanism based on the gas bubbles’ effort to minimize their surface energy. The effective performances of the devices are demonstrated.

Keywords:
microfluidics, gas bubble removal, degassing


Autoři: Sebastian Richert;  Oliver Peters;  Vu Hoa Nguyen;  Uwe Schnakenberg
Působiště autorů: Institute of Materials in Electrical Engineering 1, RWTH Aachen University, Germany
Vyšlo v časopise: Lékař a technika - Clinician and Technology No. 2, 2016, 46, 41-45
Kategorie: Původní práce

Souhrn

Unintendedly introduced gas bubbles in channels can significantly interfere with performance and behavior of microfluidic systems. Thus, there is a high demand for smart microfluidic system designs which are capable of preventing gas bubbles. In this work, we develop two different bubble interference preventing system designs: a degasser device that actively removes gas bubbles from the liquid based on pressure driven gas permeation, and a passive micro channel design that provides a guiding mechanism based on the gas bubbles’ effort to minimize their surface energy. The effective performances of the devices are demonstrated.

Keywords:
microfluidics, gas bubble removal, degassing


Zdroje

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[4] Jo, B.-H., Van Lerberghe, L. M., Motsegood, K. M., Beebe, D. J., Three-dimensional micro-channel fabrication in poly-dimethylsiloxane (PDMS) elastomer. Journal of Microelectromechanical Systems, 2000, vol. 9, no.1, p. 76-81.

[5] Merkel, T.C., Bondar, V.I., Nagai, K., Freeman, B.D., Pinnau, I., Gas sorption, diffusion, and permeation in poly(dimethyl-siloxane), Polymer Physics, 2000, vol. 38, no. 3.

[6] Baroud, C.N., Gallaire, F., Dangla, R., Dynamics of microfluidic droplets. Lab on a chip, 2010, vol. 10, p. 2032-2045.

[7] Guenther, A., Manish, J., Thalmann, M., Schmidt, A.M., Jensen, K.F., Micromixing of miscible liquids in segmented gas-liquid flow. Langmuir, 2005, vol. 21, no. 4, p. 1547-1555.

Štítky
Biomedicína
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