Guidelines for inherited thrombophilia testing in children
Authors:
K. Zdráhalová 1; P. Mazánek 2; E. Zápotocká 1; J. Blatný 2
Authors‘ workplace:
Klinika dětské hematologie a onkologie, FN Motol a Homolka, Praha
1; Oddělení dětské hematologie a biochemie, FN Brno
2
Published in:
Transfuze Hematol. dnes,32, 2026, No. 3, p. 223-225.
Category:
Best Practices
doi:
https://doi.org/10.55095/CSPediatrie2026/028
Overview
The incidence of thromboembolic disease in childhood is low compared to the adult population. Thrombophilia refers to factors that increase the risk of developing thrombosis. The most important factors in the development of thrombosis in children are acquired, with central venous catheters being the leading cause. In contrast, inherited thrombophilias play only a minor role. Approved consensus guidelines based on published literature specify the indications for testing for inherited thrombophilias and the scope of such testing. Incorrectly indicated, performed, and/or interpreted testing may be misleading and potentially harmful.
Keywords:
testing – thrombophilia – indication – childhood – thrombosis – inherited thrombophilia
Sources
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Labels
Haematology Internal medicine Clinical oncologyArticle was published in
Transfusion and Haematology Today
2026 Issue 3
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- Vascular Disease in the Gradually Aging Population of Hemophiliacs: An Underestimated Problem?
- Prognostic Significance of Subclinical Joint Changes on MRI in Hemophilia
- Immunotolerance is still the goal of management of hemophilia A with inhibitor in the era of non-factor therapy
- Minimum and Optimal Factor Levels in Physically Active Hemophiliacs
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