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The relationship between oral and overall health


Authors: I. Bryjová 1,2,5;  N. Skibová 2,4;  M. Janíková 1,3;  H. Tomášková 1,3;  M. Starosta 1
Authors‘ workplace: Ostravská univerzita, Lékařská fakulta Ústav epidemiologie a ochrany veřejného zdraví Vedoucí: doc. MUDr. Rastislav Maďar, PhD., MBA, FRCPS 1;  Slezská univerzita v Opavě, Fakulta veřejných politik Ústav nelékařských zdravotnických studií Vedoucí: doc. PhDr. Yvetta Vrublová, Ph. D. 2;  Zdravotní ústav se sídlem v Ostravě Ředitel: Ing. Eduard Ježo 3;  LUNA dental s. r. o., Moravská Ostrava a Přívoz 4;  Zubní klinika Svět úsměvů s. r. o., Háj ve Slezsku 5
Published in: Prakt. Lék. 2025; 105(5-6): 183-188
Category: Reviews

Overview

Periodontitis and dental caries are among the most prevalent chronic oral diseases worldwide. Recent evidence links these conditions to type 2 diabetes, cardiovascular and neurodegenerative diseases, osteoporosis, obesity, and adverse pregnancy outcomes. Key mechanisms involve chronic low-grade inflammation, oral microbiome dysbiosis, and translocation of oral pathogens into the systemic circulation. This review summarizes findings from a systematic search of studies published between 2015 and 2025 in the PubMed and Scopus databases, focusing on links between oral and systemic health, pathophysiological mechanisms, and clinical implications.

Keywords:

prevention – Oral health – Periodontitis – diabetes mellitus – systemic diseases


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