Molecular Prognostic Factors and Pathogenesis of Endometrial Cancer
Molekulární prognostické faktory a patogeneze endometriálního karcinomu
Cíl studie:
Zhodnocení významu molekulárně biologických markerů pro prognózu a patogenezi karcinomu endometria.
Typ studie:
Přehledný článek.
Název a sídlo pracoviště:
Ústav lékařské genetiky a fetální medicíny, LF UP a FN Olomouc, Gynekologicko-porodnická klinika, LF UP a FN Olomouc.
Metodika:
Přehledný souhrn současných poznatků o patogenetických změnách u endometriálního karcinomu na molekulární úrovni a jejich možném významu pro prognózu pacientek.
Závěr:
Nové molekulárně biologické faktory budou zřejmě hrát v blízké budoucnosti stále významnější roli v managementu léčby karcinomu endometria.
Klíčová slova:
karcinom, endometrium, marker, prognóza
Authors:
I. Míčková 1; R. Pilka 2; M. Lubušký 2; Milan Kudela 2
Authors‘ workplace:
Ústav lékařské genetiky a fetální medicíny, LF UP a FN, Olomouc, přednosta prof. MUDr. J. Šantavý, CSc.
1; Gynekologicko-porodnická klinika, LF UP a FN, Olomouc, přednosta prof. MUDr. M. Kudela, CSc.
2
Published in:
Ceska Gynekol 2006; 71(4): 355-360
Category:
Original Article
Overview
Objective:
To evaluate the importance of molecular markers for prognosis and pathogenesis of endometrial carcinoma.
Design:
A review article.
Setting:
Department of Medical Genetics and Fetal Medicine, University Hospital, Olomouc, Department of Obstetrics and Gynecology, University Hospital, Olomouc.
Methods:
This article reviews the current knowledge of the molecular changes in the development of endometrial cancer, and their possible importance for the patient’s prognosis.
Conclusion:
The new molecular biomarkers are apparently going to play a significant role in the management of endometrial carcinoma treatment in the near future.
Key words:
carcinoma, endometrium, marker, prognosis
Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineArticle was published in
Czech Gynaecology
2006 Issue 4
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