Comparison of Remifentanil and Alfentanil for Analgosedation during Colonoscopy
Srovnání účinků remifentanilu a alfentanilu při analgosedaci ke koloskopii
Endoskopická vyšetření v oblasti gastrointestinálního traktu představují pro pacienty nepříjemný a bolestivý zážitek. Analgosedace umožňuje omezitdyskomfort pacienta způsobený výkonem, a tak podstatně urychlit a usnadnit průběh výkonu. Kombinace midazolamu s remifentanilem, respektivealfentanilem, poskytla dostatečně hlubokou analgosedaci pro provedení koloskopie. Tato kombinace farmak byla doprovázena minimem nežádoucíchúèinkù. Zotavení probíhalo rychleji v souboru s remifentanilem, ale za hodinu byly výsledky v obou souborech srovnatelné. Pacienti byli propuštěniza čtyři hodiny po výkonu domů. Kombinace midazolamu s remifentanilem byla také levnější.
Klíčová slova:
ambulantní anestezie - benzodiazepiny - opiáty - zotavení - komplikace
Authors:
M. Svítek; J. Bohumínská
Authors‘ workplace:
KAR, 1. LF UK a VFN, Praha, přednosta doc. MUDr. Zdeněk Ehler, CSc.
Published in:
Anest. intenziv. Med., , 2001, č. 3, s. 112-116
Category:
Overview
Endoscopic procedures in the gastrointestinal tract represent an unpleasant and painful experience for a patient. Analgosedation allows foralleviation from dyscomfort associated with the procedure; the procedure can be performed easier and faster. Combination of midazolam withremifentanil or alfentanil, respectively, provided analgosedation deep enough for colonoscopy. This combination of drugs was associated with theleast adverse effects. Recovery was faster in the group with remifentanil; the next hour, the results were comparable in both groups. Patients weredischarged four hours after completion of the procedure. Combination of midazolam and remifentanil was also cheaper.
Key words:
ambulatory anaesthesia - benzodiazepines - opiates - recovery - complications
Labels
Anaesthesiology, Resuscitation and Inten Intensive Care MedicineArticle was published in
Anaesthesiology and Intensive Care Medicine
2001 Issue 3
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