Metformin and pregnancy
Authors:
MUC. Jan Přáda; MUDr. Kateřina Anderlová, Ph.D.
Authors‘ workplace:
Gynekologicko-porodnická klinika 1. LF UK a VFN Praha
Published in:
Prakt Gyn 2015; 19(1): 74-76
Category:
Students Articles: Review Article
Overview
Insulin has always been used a drug of choice in a treatment for pregnant women with diabetes mellitus. On the contrary, metformin and other oral hypoglycemic agents have not been used because of concerns about possible harm caused to the fetus. However, the latest studies prove that the safety of using metformin during pregnancy is equal to insulin therapy and it might even offer certain positives.
Key words:
diabetes mellitus – pregnancy – oral hypoglycemic agents – metformin
Sources
1. Kavitha N, De S, Kanagasabai S. Oral Hypoglycemic Agents in pregnancy: An Update. J Obstet Gynecol India 2013; 63(2): 82–87.
2. Centers for Disease Control and Prevention. National diabetes fact sheet: national estimates and general information on diabetes and prediabetes in the United States, 2011. Atlanta, GA: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, 2011. Dostupné z WWW: <http://www.cdc.gov/diabetes/pubs/pdf/ndfs_2011.pdf>.
3. Gui J, Liu Q, Feng L. Metformin vs Insulin in the Management of Gestational Diabetes: A Meta-Analysis. PLoS One 2013; 8(5): e64585. Dostupné z DOI: <http://doi: 10.1371/journal.pone.0064585>.
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Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineArticle was published in
Practical Gynecology
2015 Issue 1
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