Interdisciplinary recommendations for thrombophilia testing

Czech version

Authors: Eva Drbohlavová ¹; Jaromír Gumulec ²; Alena Buliková ³; Petr Dulíček ⁴; Jana Hirmerová ⁵; Radovan Malý ⁶; Ester Zápotocká ⁷; Jan Blatný ⁸; Jan Václavík ⁹; Petr Kessler ¹⁰
Authors‘ workplace: Oddělení klinické hematologie Krajské nemocnice Liberec, a. s. ¹; Klinika hematoonkologie LF OU a FN Ostrava ²; Oddělení klinické hematologie LF MU a FN Brno ³; IV. interní hematologická klinika LF UK a FN Hradec Králové ⁴; II. interní klinika LF UK a FN Plzeň ⁵; I. interní kardioangiologická klinika LF UK a FN Hradec Králové ⁶; Klinika dětské hematologie a onkologie 2. LF UK a FN Motol v Praze ⁷; Oddělení dětské hematologie a biochemie FN Brno ⁸; Interní a kardiologická klinika LF OU a FN Ostrava ⁹; Oddělení hematologie a transfuziologie Nemocnice Pelhřimov ¹⁰; Oddělení hematologie a transfuziologie Nemocnice Pelhřimov, AČeská společnost pro trombózu a hemostázu ČLS JEP, BČeská angiologická společnost ČLS JEP, CČeská internistická společnost ČLS JEP, DČeská hematologická společnost ČLS JEP ¹⁰
Published in: Čas. Lék. čes. 2025; 164: 356-360
Category: Guidelines

Společné stanovisko České společnosti pro trombózu a hemostázu ČLS JEP, České angiologické společnosti ČLS JEP, České hematologické společnosti ČSL JEP, České internistické společnosti ČLS JEP

Overview

In this interdisciplinary consensus of four medical societies dealing with thrombophilic disorders, we summarize the rules of diagnosis and care of patients with congenital or acquired thrombophilias, i.e. factors increasing the risk of venous thromboembolic disease. The primary goal is to standardize the care of these patients with respect to the rules of evidence-based medicine. The recommendations imply under which circumstances, in which clinical situations, for which patients and which tests it is useful to investigate which thrombophilias and when not. Despite the long history and very good availability of diagnostic tests for individual thrombophilias, no similar recommendation has been published in the Czech Republic.

Keywords:

Venous thromboembolism – arterial thrombosis – congenital and acquired thrombophilias – JAK2 mutation – PNH clone

Sources

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