Biological effects of ionizing radiation

Czech version

Authors: Renata Havránková ^1,2
Authors‘ workplace: Katedra zdravotnických oborů a ochrany obyvatelstva Fakulty biomedicínského inženýrství ČVUT v Praze ¹; Ústav radiologie, toxikologie a ochrany obyvatelstva Zdravotně sociální fakulty JU v Českých Budějovicích ²
Published in: Čas. Lék. čes. 2020; 159: 258-260
Category: Review Article

Overview

Ionizing radiation refers to the flow of material particles or photons of electromagnetic radiation that can ionize atoms of the environment through which it passes. At the cellular level, damage can be manifested by cell death or changing their cytogenetic information. These events can lead to adverse tissue reactions (deterministic effects) in which manifestations depend on exceeding the dose threshold, or to the stochastic effects, when the probability of damage increases with the dose. This article briefly summarizes these effects on the human body.

Keywords:

Ionizing radiation – biological effect – DNA damage – tissue reaction – stochastic effect

Sources

Havránková R (ed.). Klinická radiobiologie. Grada, Praha, 2020.
Gudkov IM, Vinichuk MM. Radiobiology & Radioecology. National Agricultural University of Ukraine, Kyjev, 2006.
Klener P et al. Principy a praxe radiační ochrany. Azin, Praha, 2000.
Havránková R a kol. Základy radiobiologie. ZSF JU, České Budějovice, 2018.
Feltl D, Cvek J. Klinická radiobiologie. Tobiáš, Havlíčkův Brod, 2008.
Podzimek F. Radiologická fyzika. Fyzika ionizujícího záření. ČVUT, Praha, 2015.
SÚJB. Stručný přehled biologických účinků záření. Dostupné na: www.sujb.cz/radiacni-ochrana/oznameni-a-informace/strucny-prehled-biologickych-ucinku-zareni
Kuna P, Navrátil L. Klinická radiobiologie. Manus, Praha, 2005.
Österreicher J, Vávrová J. Přednášky z radiobiologie. Manus, Praha, 2003.
ICRP. Doporučení Mezinárodní komise radiologické ochrany 2007. ICRP, 2007; 37 : 2–4.
UNEP. Ionizující záření. Účinky a Zdroje. Program OSN pro ochranu životního prostředí. UNEP, 2016.

Labels

Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental Hygienist

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