Treatment Options in Sarcoidosis
Současné možnosti léčby sarkoidózy
Kdy a čím léčit sarkoidózu? Lékem první volby jsou nadále glukokortikoidy používané v indikovaných případech buď celkově, nebo inhalačně, eventuálně lokálně u kožních forem onemocnění. Stále se také uplatňují imunosupresiva, cytostatika a antimalarika. Novějším trendem v léčbě tohoto multiorgánového granulomatózního onemocnění neznámého původu jsou inhibitory TNF – pentoxifyllin, infliximab, adalimumab, leflunomid, thalidomid.
Klíčová slova:
léčba sarkoidózy, glukokortikoidy, inhibitory TNFα, pentoxifyllin, infliximab, adalimumab, leflunomid, thalidomid.
Authors:
A. Slováková; V. Votava; J. Homolka
Authors‘ workplace:
I. klinika tuberkulózy a respiračních nemocí 1. LF UK a VFN, Praha
Published in:
Čas. Lék. čes. 2007; 146: 922-924
Category:
Review Article
Overview
When to start the treatment of sarcoidosis and what are the optimal treatment methods? The curative of the first choice are glucocorticoids used in indicated cases in general administration, as inhalation therapy or locally in the skin manifestations. Frequently used are also immunosuppressives, cytostatics and antimalarics. The newest trend in the treatment of this multi-organ granulomatose disease of unknown origin is the use of TNF inhibitors – pentoxifyllin, infliximab, adalimumab, leflunomid, thalidomid.
Key words:
sarcoidosis, glucocorticoid, TNFα inhibitors, pentoxifyllin, infliximab, adalimumab, leflunomid, thalidomide.
Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental HygienistArticle was published in
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