Telomere Analysis of Tumor Cells by in situ Techniques
Analýza telomer nádorových buněk technikami in situ
Udržování stabilních délek telomer je nezbytné pro neomezenou proliferaci zárodečných a nádorových buněk.Většinou je zajišťováno nukleoproteinovým enzymovým komplexem telomeráza, což v nádorových buňkách vedeke stabilizaci délek telomer zkrácených na
Klíčová slova:
telomery, FISH, fiber-FISH, PRINS.
Authors:
M. Skleničková 1; J. Fajkus 1
Authors‘ workplace:
Biofyzikální ústav AV ČR, Brno 2Laboratoř funkční genomiky a proteomiky MU, Brno
1
Published in:
Čas. Lék. čes. 2003; : 479-482
Category:
Overview
Stable telomere maintenance is essential for the indefinite cellular proliferation of germline and tumour cells. Inmost cases, telomere synthesis is performed by nucleoprotein enzyme complex of telomerase, that results instabilisation of telomeres shortened to
Key words:
telomeres, FISH, fiber-FISH, PRINS.
Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental HygienistArticle was published in
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