Recommendation of the Czech society of Endocrinology for the treatment of Cushing’s syndrome in adults
Authors:
M. Kršek 1; J. Čáp 2; V. Hána 1; J. Marek Za Výbor České Endokrinologické Společnosti České Lékařské Společnosti J. E. Purkyně 1
Authors‘ workplace:
III. interní klinika – klinika endokrinologie a metabolizmu 1. lékařské fakulty UK a VFN Praha, přednosta prof. MU Dr. Štěpán Svačina, DrSc., MBA
1; IV. interní hematologická klinika Lékařské fakulty UK a FN Hradec Králové, přednosta doc. MU Dr. Pavel Žák, Ph. D.
2
Published in:
Vnitř Lék 2013; 59(9): 819-827
Category:
Guidelines
Overview
Cushing’s syndrome is a rare disorder with variable aetiology which is connected with significantly increased morbidity and mortality. Therefore, early determination of correct aetiology and early treatment are essential for a decrease of morbidity and mortality of patients. Present article introduces review and current recommendation of Czech Society of Endocrinology for the treatment of Cushing’s syndrome.
Key words:
Cushing’s syndrome – treatment – recommendation
Sources
1. Cushing HW. The basophil adenomas of the pituitary body and their clinical manifestations (pituitary basophilism). Bull Johns Hopkins Hosp 1932; 50 : 137 – 195.
2. Lahera Vargas M, da Costa CV. Prevalence, etiology and clinical findings of Cushing’s syndrome. Endocrinol Nutr 2009; 56 : 32 – 39.
3. Bertagna X, Guignat L, Groussin L et al. Cushing’s disease. Best Pract Res Clin Endocrinol Metab 2009; 23 : 607 – 623.
4. Ross EJ, Linch DC. Cushing’s syndrome ‑ Killing disease: Discriminatory value of signs and symptoms aiding early diagnosis. Lancet 1982; 2 : 646 – 649.
5. Newell‑Price J, Trainer P, Bessser M et al. The diagnosis and differential diagnosis of Cushing’s syndrome and pseudo ‑ Cushing’s states. Endocr Rev 1998; 19 : 647 – 672.
6. Nieman LK, Chrousos GP, Kellner C et al. Successful treatment of Cushing’s syndrome with the glucocorticoid antagonist RU 486. J Clin Endocrinol Metab 1985; 61 : 536 – 540.
7. Nieman LK, Biller BM, Findling JW et al. The Diagnosis of Cushing’s Syndrome: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2008; 93 : 1526 – 1540.
8. Utz AL, Swearingen B, Biller BM. Pituitary surgery and postoperative management in Cushing’s disease. Endocrinol Metab Clin North Am 2005; 34 : 459 – 478.
9. McCance DR, Besser M, Atkinson AB. Assessment of cure after transsphenoidal surgery for Cushing’s disease. Clin Endocrinol 1996; 44 : 1 – 6.
10. Vladyka V, Liščák R, Šimonová G et al. Radiosurgical treatment of hypophyseal adenomas with the gamma knife: results in a group of 163 patients during a 5‑year period. Čas Lék Česk 2000; 139 : 757 – 766.
11. de Bruin C, Feelders RA, Lamberts SW et al. Somatostatin and dopamine receptors as targets for medical treatment of Cushing’s syndrome. Rev Endocr Metab Disord 2009; 10 : 91 – 102.
12. Kam BL, Teunissen JJ, Krenning EP et al. Lutetium ‑ labelled peptides for therapy of neuroendocrine tumours. Eur J Nucl Med Mol Imaging 2012; 39 (Suppl 1): 103 – 112.
13. Valimaki M, Pelkonen R, Porkka L et al. Long‑term results of adrenal surgery in patients with Cushing’s syndrome due to adrenocortical adenoma. Clin Endocrinol (Oxf) 1984; 20 : 229 – 236.
14. Young WF Jr, Thompson GB. Laparoscopic adrenalectomy for patients who have Cushing’s syndrome. Endocrinol Metab Clin North Am 2005; 34 : 489 – 499.
15. Berruti A, Terzolo M, Sperone P et al. Etoposide, doxorubicin and cisplatin plus mitotane in the treatment of advanced adrenocortical carcinoma: a large prospective phase II trial. Endocr Relat Cancer 2005; 12 : 657 – 666.
16. Fassnacht M, Libé R, Kroiss M et al. Adrenocortical carcinoma: a clinician’s update. Nature Rev Endocrinol 2011; 7 : 323 – 335.
17. McGahan J, Browning P, Brock J et al. Hepatic ablation using radiofrequency electrocautery. Invest Radiol 1990; 25 : 267 – 270.
18. de Baere T, Dufaux J, Roche A et al. Circulatory alterations induced by intra ‑ arterial injection of iodized oil and emulsions of iodized oil and doxorubicin: experimental study. Radiology 1995; 194 : 165 – 170.
19. Bourdeau I, Lacroix A. Aberrant hormone receptors in adrenal Cushing’s syndrome. Curr Opin Endocrinol Diab 2002; 9 : 230 – 236.
20. Morris D, Grossman A. The medical management of Cushing’s syndrome. Ann NY Acad Sci 2002; 970 : 119 – 133.
21. Godboud A, Manavela M, Danilowicz K et al.Cabergoline monotherapy in the long‑term treatment of Cushing’s disease. Eur J Endocrinol 2010; 165 : 709 – 716.
22. Casulari LA, Naves LA, Mello PA et al. Nelson’s syndrome: complete remission with cabergoline but not with bromocriptine or cyproheptadine treatment. Horm Res 2004; 62 : 300 – 305.
23. Pivonello R, Ferrone D, de Herder WW et al. Dopamine receptor expression and function in corticotroph ectopic tumors. J Clin Endocrinol Metab 2007; 92 : 65 – 69.
24. Valassi E, Klibanski A, Biller BM. Clinical review: Potential cardiac valve effects of dopamine agonists in hyperprolactinemia. J Clin Endocrinol Metab 2010; 95 : 1025 – 1033.
25. Lamberts SW, Uitterlinden P, Klijn JM. The effect of the long‑acting somatostatin analogue SMS 201 – 995 on ACTH secretion in Nelson’s syndrome and Cushing’s disease. Acta Endocrinol (Copenh) 1989; 120 : 760 – 766.
26. Hofland LJ, van der Hoek J, Feelders R et al.The multiligand somatostatin analogue SOM230 inhibits ACTH secretion by cultured human corticotroph adenomas via somatostatin receptor type 5. Eur J Endocrinol 2005; 152 : 645 – 654.
27. Colao A, Petersenn S, Newell‑Price J et al. Pasireotide B2305 Study Group. A 12-month phase 3 study of pasireotide in Cushing’s disease. N Engl J Med 2012; 366 : 914 – 924.
28. Castillo V, Giacomini D, Paez ‑ Pereda M et al.Retinoic acid as a novel medical therapy for Cushing’s disease in dogs. Endocrinology 2006; 147 : 4438 – 4444.
29. Dang CN, Trainer P. Pharmacological management of Cushing’s syndrome: an update. Arq Bras Endocrinol Metabol 2007; 51 : 1339 – 1348.
30. Knight TE, Shikuma CY, Knight J. Ketoconazole‑induced fulminant hepatitis necessitating liver transplantation. J Am Acad Dermatol 1991; 25 : 398 – 400.
31. Verhelst JA, Trainer PJ, Howlett TA et al. Short and long‑term responses to metyrapone in the medical management of 91 patients with Cushing’s syndrome. Clin Endocrinol (Oxf) 1991; 35 : 169 – 178.
32. Haak HR, Hermans J, van de Velde CJ et al. Optimal treatment of adrenocortical carcinoma with mitotane: results in consecutive series of 96 patients. Br J Cancer 1994; 69 : 947 – 951.
33. Allolio B, Schulte HM, Kaulen D et al. Nonhypnotic low‑dose etomidate for rapid correction of hypercortisolaemia in Cushing’s syndrome. Klin Wochenschr 1988; 66 : 361 – 364.
34. Drake WM, Perry LA, Hinds CJ et al. Emergency and prolonged use of intravenous etomidate to control hypercortisolaemia in a patient with Cushing’s syndrome and peritonitis. J Clin Endocrinol Metab 1998; 83 : 3542 – 3544.
35. Feelders RA, de Bruin C, Pereira AM et al. Pasireotide alone or with cabergoline and ketoconazole in Cushing’s disease. N Engl J Med 2010; 362 : 1846 – 1848.
36. Kršek M, Hána V et al. Cushingův syndrom. Praha: Galén 2006.
37. Kršek M. Cushingův syndrom a možnosti jeho řešení v roce 2012. Remedia 2012; 22 : 386 – 392.
38. Trainer PJ, Eastment C, Grossman A et al. The relationship between cortisol production rate and serial serum cortisol estimation in patients on medical therapy for Cushing’s syndrome. Clin Endocrinol 1993; 39 : 441 – 443.
39. Lindsay JR, Jonklaas J, Oldfield EH et al. Cushing’s syndrome during pregnancy: personal experience and review of the literature. J Clin Endocrinol Metab 2005; 90 : 3077 – 3083.
Labels
Diabetology Endocrinology Internal medicineArticle was published in
Internal Medicine
2013 Issue 9
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