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Diplopia as the first manifestation of multiple sclerosis


Authors: V. Ragénaité-Mrnka -
Authors‘ workplace: Fakultní nemocnice v Olomouci, Oddělení praktického lékařství, Vedoucí: MUDr. Viktorija Ragénaité-Mrnka 1;  Univerzita Palackého v Olomouci, Lékařská fakulta, Ústav veřejného zdravotnictví Přednostka: prof. MUDr. Dagmar Horáková, Ph.D. 2
Published in: Prakt. Lék. 2026; 106(1): 34-37
Category: Case Report

Overview

This case shows how a single symptom can lead to the diagnosis of an incipient disease. A 26-year-old female teacher had prolonged diplopia after a head trauma. Her general practitioner did not hesitate to order a neurological examination, including an MRI of the head, which proved the suspicion of multiple sclerosis. After a thorough neurological examination, including a cerebrospinal fluid examination, in which pattern II –⁠ positive oligoclonal synthesis of IgG in the CNS was strongly expressed, multiple sclerosis was finally diagnosed. And the patient was provided with early and effective treatment.

Keywords:

Head injury – Multiple sclerosis – general practitioner – differential diagnosis – diplopia – mild traumatic brain injury (mTBI)


Sources

1. Růžička E, a kol. Neurologie, 3. rozšířené vydání. Praha: Triton 2019; 278;287.

2. Pipek LZ, Mahler JV, Nascimento RFV, et al. Cost, efficacy, and safety comparison between early intensive and escalating strategies for multiple sclerosis: a systematic review and meta-analysis. Mult Scler Relat Disord. 2023; 71 : 104581.

Labels
General practitioner for children and adolescents General practitioner for adults

Article was published in

General Practitioner

Issue 1

2026 Issue 1
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