Advances in the pharmacological treatment of schizophrenia
Pokroky ve farmakologické léčbě schizofrenie
Článek shrnuje možnosti diagnostiky schizofrenie a její léčbu. Krátce je shrnuta historie antipsychotik (AP). V současné době jsou preferována atypická AP. Jejich dostupnost (včetně dlouhodobě působících) zvyšuje compliance, která je nezbytnou podmínkou dosažení a udržení remise. Remise schizofrenní poruchy se stává hlavním cílem léčby. Jednotlivá atypická AP se liší ve vedlejších účincích, což zohledňujeme při volbě AP pro konkrétního nemocného. Na základě současných znalostí je nutné přistupovat k léčbě komplexně a je nutné zohlednit psychický i tělesný stav nemocného.
Klíčová slova:
léčba antipsychotiky – atypická antipsychotika – compliance – remise – vedlejší účinky – volba antipsychotika.
Authors:
E. Češková
Authors‘ workplace:
Psychiatrická klinika LF MU a FN, Brno
přednostka prof. MUDr. E. Češková, CSc.
Published in:
Prakt. Lék. 2005; 85(11): 614-617
Category:
Various Specialization
Overview
The article summarizes the possibilities of diagnosis and treatment of schizophrenia. Shortly the history of antipsychotics (AP) is reviewed. Nowadays the atypical APs are preferred. Their availability (including long-acting atypical AP) enhances compliance, which is the necessary condition for the achievement and maintenance of remission. The remission is becoming the main aim of the treatment. The individual atypical agents differ in their side effects and this should be taken into consideration when choosing AP for an individual patient. On the base of present knowledge it is obligatory to use a complex approach and consider not only the psychic but also the somatic state of the patient.
Key words:
antipsychotic treatment – atypical antipsychotics – compliance – remission – side effects – choice of antipsychotic.
Labels
General practitioner for children and adolescents General practitioner for adultsArticle was published in
General Practitioner
2005 Issue 11
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