Long-term Infliximab Maintenance Therapy for Ulcerative Colitis  
The ACT-1 and ACT-2 Extension Studies
							
			
			
																	
									Authors:
											M. Lukáš							
								
							
																
				
									Authors‘ workplace:
											Klinické a výzkumné centrum pro střevní záněty, ISCARE a 1. LF UK v Praze a Ústav klinické biochemie a laboratorní diagnostiky, 1. LF UK v Praze
																
				
									Published in:
					Gastroent Hepatol 2012; 66(4): 286-288
					
				
									Category:
					Commentary
					
				
							
Sources
1. Reinisch W, Sandborn WJ, Rutgeerts P et al. Long-term infliximab maintenance therapy for ulcerative colitis: the ACT-1 and -2 extension studies. Inflamm Bowel Dis 2012; 18(2): 201–211.
2. Rutgeerts P, Sandborn WJ, Feagan BG et al. Infliximab for induction and maintenance therapy for ulcerative colitis. N Engl J Med 2005; 353(23): 2462–2476.
3. Sandborn WJ, Rutgeerts P, Feagan BG et al. Colectomy rate comparison after treatment of ulcerative colitis with placebo or infliximab. Gastroenterology 2009; 137(4): 1250–1260.
4. Reinisch W. Biologic therapy of ulcerative colitis: Infliximab, Adalimumab, Golimumab. In: Crohn’s disease and ulcerative colitis: from epidemiology and immunobiology to a rational diagnostic and therapeutic approach. New York: Springer Science+Business Media LLC 2012.
5. Feagan BG, Reinisch W, Rutgeerts P et al. The effects of infliximab therapy on health-related quality of life in ulcerative colitis patients. Am J Gastroenterol 2007; 102(4): 794–802.
6. Pannacione R, Ghosh S, Middleton S et al. Infliximab, Azathioprine, or Infliximab + Azathioprine for treatment of moderate to severe ulcerative colitis. The UC SUCCESS trial. Gastroenterology 2011; 140 (Suppl 1): S134.
7. Fidder H, Schnitzler F, Ferrante M et al. Long-term safety of infliximab for the treatment of inflammatory bowel disease: a single-centre cohort study. Gut 2009; 58(4): 501–508.
8. Travis SP, Stange EF, Lémann M et al. European Crohn’s and Colitis Organisation (ECCO). European evidence-based Consensus on the management of ulcerative colitis: Current management. J Crohns Colitis 2008; 2(1): 24–62.
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Paediatric gastroenterology Gastroenterology and hepatology SurgeryArticle was published in
Gastroenterology and Hepatology
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