Which non-steroidal anti-inflammatory drug should be used in patients with increased risk of gastrointestinal toxicity?
Commentary on CONDOR study
							
			
			
																	
									Authors:
											M. Bortlík						1,2; 											M. Lukáš						1,3							
								
							
																
				
									Authors‘ workplace:
											Klinické a výzkumné centrum pro střevní záněty, ISCARE a 1. LF UK v Praze
						1; 											Interní klinika, 1. LF UK a ÚVN Praha
						2; 											Ústav klinické biochemie a laboratorní diagnostiky, 1. LF UK v Praze
						3										
				
									Published in:
					Gastroent Hepatol 2011; 65(3): 159-160
					
				
									Category:
					Commentary
					
				
							
Sources
1. Lukáš M, Chalupná P, Adamec S et al. Adverse effects of non-steroidal antirheumatic agents on the digestive tract. Sb Lek 2002; 103(2): 265–272.
2. Ng SC, Chan FLK. NSAID-induced gastrointestinal and cardiovascular injury. Curr Opin Gastroenterol 2010; 26(6): 611–617.
3. Chan FKL, Lanas A, Scheiman J et al. Celecoxib versus omeprazole and diclofenac in patients with osteoarthritis and rheumatoid arthritis (CONDOR): a randomised trial. Lancet 2010; 376(9736): 173–179.
4. Spiegel BMR, Farid M, Dulai GS et al. Comparing rates of dyspepsia with coxibs vs NSAID+PPI: a meta-analysis. Am J Med 2006; 119(5): 448.
Labels
Paediatric gastroenterology Gastroenterology and hepatology SurgeryArticle was published in
Gastroenterology and Hepatology
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