Malignant Fibrous Histiocytoma of the Breast: Report of Two Cases

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Maligní fibrózní histiocytom prsu –⁠ popis 2 případů

Prezentace dvou případů maligního fibrózního histiocytomu prsu –⁠ u 63leté ženy, kde se jednalo o myxoidní typ MFH, a u 79leté ženy s MFH pleiomorfního typu. Maligní fibrózní histiocytom je jeden z nejčastějších maligních tumorů měkkých tkání, jeho primární výskyt v mléčné žláze je však vzácný. Imunohistochemický průkaz antigenů v cytoplazmě histiocytů pomocí protilátky LN 5 (Anti-Macrofage, BioGenex) může pomoci ke stanovení správné diagnózy.

Klíčová slova:
maligní fibrózní histiocytom –⁠ mamma –⁠ imunohistochemie

Authors: Z. Pavlovský; E. Jandáková; D. Stratil; S. Hotárková
Authors‘ workplace: Patologicko-anatomický ústav FN, Brno-Bohunice
Published in: Čes.-slov. Patol., 42, 2006, No. 1, p. 39-42
Category:

Overview

Two cases of malignant fibrous histiocytoma (MFH) of the breast are presented. The first case was a 63-year-old patient with MFH of myxoid type, the second case was a 79-year-old patient with MFH of pleiomorphic type. MFH is one of the most common tumors of the soft tissues, but its primary occurrence in the breast is rare. Immunohistochemical detection of antigens in the cytoplasm of histiocytes by antibdy LN 5 (Anti-Macrophage, BioGenex) can be helpful in rendering of the right diagnosis.

Key words:
malignant fibrous histiocytoma –⁠ breast –⁠ immunohistochemistry

Labels

Anatomical pathology Forensic medical examiner Toxicology

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Article was published in

Czecho-Slovak Pathology

2006 Issue 1