Year-Long Sublingual Allergen Immunotherapy in Children with Pollinosis
Celoročná sublingválna alergénová imunoterapia u detí s polinózou
V súčasnosti je alergénová imunoterapia (AIT) jediným kauzálnym zásahom ovplyvňujúcim priebeh alergickéhoochorenia. Je založená na aplikácii stúpajúceho množstva alergénu, na ktorý je pacient precitlivelý s cieľomdosiahnuť dávku, ktorá je efektívna pri oslabení (ústupe) symptómov vyvolaných kontaktom s kauzálnym alergénom.Je indikovaná u pacientov s alergickou rinitídou, konjunktivitídou a s alergiou na uštipnutie hmyzom.V minulosti sa imunoterapia alergénmi podávala parenterálne. V posledných rokoch sa do popredia dostávalokálna (najmä sublingválna) aplikačná forma.Autori uvádzajú vlastné skúsenosti s celoročnou sublingválnou AITStaloralom u 26 pacientov s prejavmi polinózy. Sledovaním prejavov ochorenia počas peľovej sezóny zaznamenaliuž v druhom roku liečby štatisticky významný pokles výskytu očných (p
Klíčová slova:
alergénová imunoterapia, indikácie a kontraindikácie, polinóza, deti
Authors:
Z. Kuková; A. Kotzigová; L. Kovács
Authors‘ workplace:
II. detská klinika LFUK a DFNsP, Bratislava prednosta prof. MUDr. L. Kovács, DrSc., MPH.
Published in:
Čes-slov Pediat 2003; (12): 754-756.
Category:
Overview
At the present time allergen immunotherapy (AIT) is the only causal intervention influencing the course ofallergic disease. It is based on the application of increasing amounts of allergen to which the patient is oversensitivewith the aim to reach the dose, which is effective in reaching diminution (disappearance) of symptoms caused bya contact with the causal allergen. The treatment is indicated in patients with allergic rhinitis, conjunctivitis andin allergy to insect bite. In previous time the immunotherapy with allergens was administered parenterally. In thelast years increasing attention is paid to local (especially sublingual) route of administration. The authors describetheir own experience in one-year sublingual AIT with Staloralon in 26 patients affected by manifestations ofpollinosis. The monitoring of the disease manifestations during the pollen season revealed a significant decrease inthe occurrence of ocular (P
Key words:
allergen immunotherapy, indication and contraindication, pollinosis, children
Labels
Neonatology Paediatrics General practitioner for children and adolescentsArticle was published in
Czech-Slovak Pediatrics
2003 Issue 12
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