Total Antioxidant Capacity in Female Patients with Rheumatoid Arthritis
Celková antioxidační kapacita pacienteks revmatoidní artritidou
Revmatoidní artritida je zánětlivé onemocnění, v jejíž patogenezi hrají roli i re aktivní formy kyslíku. Ke kompenzaci chronického oxidačního stresu je nutná správná funkce antioxidační obrany.Pro objasnění její role změřil autor antioxidační kapacitu u 120 pacientek s revmatoidní artritidoua 51 žen kontrolní skupiny. Antioxidační kapacita byla změřena soupravou firmy Randox za použitímetody ABTS. Průměrná hodnota antioxidační kapacity u pacientů s revmatoidní art ritidou byla1,581±0,131 mmol/l, u členů kontrolní skupiny 1,666±0,136 mmol/l a rozdíl je vysoce statistickyvýznamný (p
Klíčová slova:
celková antioxidační kapacita, revmatoidní artritida
Authors:
V. Kutal
Authors‘ workplace:
Soukromá revmatologická ambulance, Brno
Published in:
Čes. Revmatol., , 2002, No. 1, p. 7-10.
Category:
Overview
Rheumatoid arthritis is an inflammatory disease in the pathogenesis of which an important part isplayed also by reactive forms of oxygen. For compensation of chronic oxidation stress properfunctioning of antioxidant defence is needed. To elucidate its role the author assessed the antioxi-dant capacity in 120 patients with rheumatoid arthritis and 51 controls. The antioxidant status wasmeasured by a set provided by Randox Co. using the ABTS method. The mean value of theantioxidant capacity in patients with rheumatoid arthritis was 1.581±1.31 mmol/l, in members of thecontrol group 1.666±0.136 mmol/l and the difference was highly significant ( p
Key words:
total antioxidant status, rheumatoid arthritis
Labels
Dermatology & STDs Paediatric rheumatology RheumatologyArticle was published in
Czech Rheumatology
2002 Issue 1
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