Breast Carcinoma with Three Coexistant Type of Metaplasia: Sarcomatoid, Giant Cell and Squamous Differantiation
Karcinom prsu s přítomností tří typů metaplazie: sarkomaloidní, velkobuněčná a dlaždicová diferenciace
Autoři popisují nález metastatického karcinomu u ženy v pravém prsu. Po určení diagnózy byla provedena jednoduchá mastektomie. Histologické a imunohistochemické vyšetření bylo provedeno z bioptického materiálu. Převažoval nález bizarních, maligních obrovských buněk a difuzní zánětlivé změny. Současně byla zjištěna přítomnost sarkomatózní metaplazie a skvamózní metaplazie. Nebyl nalezen žádný okrsek klasického intraduktálního, či invazivnho duktálního, lobulárního nebo papilárního karcinomu. Pacientka je pět po operaci a bez obtíží. Popsán neobvyklý případ a diskutován ve vztahu k literárním zdrojům.
Klíčová slova:
karcinom prsu, metaplastický karcinom, protinádorová léčba
Authors:
K. O. Belenli 1; F. Markoć 2; A. Saglam 3; S. Cukur 1; M. Alper 1
Authors‘ workplace:
Abant Izzet Baysal University, Dept of Pathology, Duzce School of Medicine Duzce/Turkey
1; Dept of Pathology Ankara Oncology Hospital, Ankara/Turkey
2; Departments of General Surgery Haydarpasa Numune Hospital Istanbul/Turkey
3
Published in:
Ceska Gynekol 2006; 71(1): 40-43
Category:
Original Article
Overview
We report on a women with metaplastic carcinoma of the right breast. After diagnosis she had a simple mastectomy operation. Pathological investigations were carried out on mastectomy material. Immunohistochemical analyses were performed. Bizarre, malignant giant cells and diffuse inflammatory reactions were predominantly noted. Sarcomatous metaplasia and rare squamous metaplasia were also seen. There was not any area of classic intraductal, invasive ductal, lobular or papillary carcinoma. The patient is still alive and well for more than five years. This uncommon case is described and discussed, and the related literature is reviewed.
Key words:
breast, metaplastic carcinoma, giant cell, sarcomatous metaplasia
Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineArticle was published in
Czech Gynaecology
2006 Issue 1
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