Proteomics and its Importance for GynecologicalOncology
Proteomics a jeho význam progynekologickou onkologii
Cíl studie:
Přehled současných znalostí o proteomics a jeho využití v diagnostice karcinomu ovariaa jiných zhoubných nádorů.Typ studie: Přehledový článek.Název a sídlo pracoviště: Gynekologicko-porodnická klinika 1. LF UK a VFN, Praha.Metodika: Přehled publikovaných dat.Závěr: Proteomics se zabývá analýzou bílkovin přítomných v organismu za normálních i patologickýchpodmínek. Exprese proteinů je charakteristická pro jednotlivé typy buněk a tkání. Hlavnímvyužitím analýzy bílkovin v klinické praxi je časná diagnostika onkologických onemocněnía zpřesnění jejich prognózy.
Klíčová slova:
proteomics, karcinom ovaria
Authors:
J. Lacheta; D. Cibula; P. Freitag; J. Živný
Authors‘ workplace:
Gynekologicko-porodnická klinika 1. LF UK a VFN, Praha, přednosta prof. MUDr. J. Živný, DrSc.
Published in:
Ceska Gynekol 2004; (5): 0
Category:
Overview
Objective:
Analysis of contemporary knowledge of proteomics and its aplication in diagnostics ofovarian cancer and other malignant tumours.Design: Review article.Setting: Department of Gynecology and Obstetrics, 1st Faculty of Medicine, Charles University,Prague.Method: An overview of published data.Conclusion: Proteomics deals with the analysis of proteins present in the organism in normal andpathologic conditions. Protein expression is characteristic of particular types of cells and tissues.The main improvement of protein analysis in clinical practice is early diagnostics of oncologicaldiseases and specifi cation of prognosis.
Key words:
proteomics, ovarian cancer
Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineArticle was published in
Czech Gynaecology
2004 Issue 5
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