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A Neurological Complication of Hepatitis E –  a Case Study


Authors: L. Petroušová 1;  L. Rožnovský 1;  J. Mrázek 2;  A. Kloudová 2;  P. Vašíčková 3;  I. Woznicová 4
Authors‘ workplace: Klinika infekčního lékařství LF OU a FN Ostrava 1;  Oddělení molekulární biologie, Zdravotní ústav se sídlem v Ostravě 2;  Výzkumný ústav veterinárního lékařství, v. v. i., Brno 3;  Neurologická klinika LF OU a FN Ostrava 4
Published in: Cesk Slov Neurol N 2015; 78/111(2): 220-222
Category: Case Report

Overview

Neurological complications of acute hepatitis E are relatively rare. The case report describes mono­neuropatia multiplex with aseptic meningitis in a 52‑year ‑⁠ old immunocompetent man. Viral hepatitis E was confirmed serologically and by polymerase chain reaction from the blood and cerebrospinal fluid (genotype 3f). Symp­tomatic treatment was given. Residual neurological deficit persisted six months after the onset of the disease. Dia­gnostic of hepatitis E should be considered in patients with concurrent neurological symp­toms and liver cytolysis.

Key words:
hepatitis E –⁠ mononeuropatia multiplex

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.


Sources

1. Trmal J, Pavlík I, Vašíčková P, Matějíčková L, Šimůnková L,Luks S et al. Epidemie virové hepatitidy E v České republice? Epidemiol Mikrobio­l Imunol 2012; 61(1 –⁠ 2): 15 –⁠ 20.

2. Wedemeyer H, Pischke S, Manns MP. Pathogenesis and treatment of hepatitis E virus infection. Gastroenterology 2012; 142(6): 1388 –⁠ 1397. doi: 10.1053/ j.gastro.2012.02.014.

3. Kamar N, Bendall RP, Peron JM, Cintas P, Mansuy JM,Rostaing L et al. Hepatitis E virus and neurologic disorders. Emerg Infect Dis 2011; 17(2): 173 –⁠ 179. doi: 10.3201/ eid1702.100856.

4. Chalupa P, Holub M. Jaundice complicated by an atypical form of Guillain‑Barré syndrome. J Clin Virol 2010; 49(4): 229 –⁠ 230. doi: 10.1016/ j.jcv.2010.07.017.

5. Despierres LA, Kaphan E, Attarian S, Cohen ‑⁠ Bacrie S, Pelletier J, Pouget J et al. Neurologic disorders and hepatitis E, France, 2010. Emerg Infect Dis 2011; 17(8): 1510 –⁠ 1512. doi: 10.3201/ eid1708.102028.

6. Tse A, Cheung R, Ho SL, Chan KH. Guillain‑Barré syndrome associated with acute hepatitis E infection. J Clin Neurosci 2012; 19(4): 607 –⁠ 608. doi: 10.1016/ j.jocn.2011.06.024.

7. Scharn N, Ganzenmueller T, Wenzel JJ, Dengler R, Heim A, Wegneret F. Guillain‑Barré syndrome associated with autochthonous infection by hepatitis E virus subgenotype 3c. Infection 2014; 42(1): 171 –⁠ 173. doi: 10.1007/ s15010 ‑⁠ 013 ‑⁠ 0448 ‑⁠ 5.

8. Moisset X, Vitello N, Bicilli E, Courtin R, Ferrier A, Taithe Fet al. Severe bilateral amyotrophic neuralgia associated with major dysphagia secondary to acute hepatitis E. F1000Res 2013; 2 : 259. doi: 10.12688/ f1000research.2 ‑⁠ 259.v2.

9. Santos L, Mesquita JR, Rocha Pereira N, Lima ‑⁠ Alves C, Serrão R, Figueiredo P et al. Acute hepatitis E complicated by Guillain‑Barré syndrome in Portugal, December 2012 –⁠ a case report. Euro Surveill 2013; 18(34): 20563.

10. Maurissen I, Jeurissen A, Strauven T, Sprengers D,De Schepperal B. First case of anti‑ganglioside GM1 -⁠ positive Guillain‑Barré syndrome due to hepatitis E virus infection. Infection 2012; 40(3): 323 –⁠ 326. doi: 10.1007/ s15010 ‑⁠ 011 ‑⁠ 0185 ‑⁠ 6.

Labels
Paediatric neurology Neurosurgery Neurology

Article was published in

Czech and Slovak Neurology and Neurosurgery

Issue 2

2015 Issue 2
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