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Treatment of anaemia and iron deficiency in chronic heart failure


Authors: J. Vítovec 1;  J. Špinar 2,3;  L. Špinarová 1
Authors‘ workplace: I. interní kardioangiologická klinika LF MU a FN u sv. Anny v Brně 1;  Interní kardiologická klinika LF MU Brno 2;  Mezinárodní centrum klinického výzkumu, Brno 3
Published in: Kardiol Rev Int Med 2014, 16(5): 364-369
Category: Cardiology Review

Overview

Iron deficiency is an important co ‑⁠ morbidity in patients with heart failure. A major factor in the pathogenesis of anaemia, it is also a separate condition with serious clinical consequences (e. g. impaired exercise capacity) and poor prognosis in heart failure patients. Experimental evidence suggests that iron therapy in iron ‑⁠ deficient patients may activate molecular pathways that can be cardio ‑⁠ protective. Clinical studies have demonstrated favourable effects of IV iron on the functional status, quality of life, and exercise capacity in HF patients. IV iron supplementation has become a novel therapy in HF patients with iron deficiency.

Keywords:
anaemia –⁠ iron deficiency –⁠ heart failure –⁠ therapy of anaemia


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Labels
Paediatric cardiology Internal medicine Cardiac surgery Cardiology
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