Impact of the opening manoeuvre on gas exchange, haemodynamics and the splanchnic circulation in ARDS patients
Vliv otevíracího manévru na výměnu plynů, hemodynamiku a splanchnickou cirkulaci u ARDS pacientů
Cíl:
Provést otevírací manévr (OM) u ARDS podle transalveolárního tlaku (Ptrans) a zhodnotit vliv na celkovou a splanchnickou cirkulaci a na výměnu plynů.
Typ studie:
Prospektivní, intervenční studie.
Název a sídlo pracoviště:
Anesteziologicko-resuscitační klinika FN u sv. Anny v Brně.
Soubor a metody:
Zařazeni pacienti v časné fázi ALI/ARDS. OM proveden v režimu CPAP, trvání 40 s; cílem bylo dosažení Ptrans 30 cm H₂O monitorovaného speciálním monitorovacím systémem. Dvě minuty před OM (preOM), 2 a 30 minut po OM (OM2, OM30) byly měřeny hemodynamické parametry, analyzovány krevní plyny z a. pulmonalis, a. radialis av. hepatica. Významnost změn byla hodnocena Friedmanovým ANOVA testem. Data jsou vyjádřena jako medián a rozpětí kvartilů.
Výsledky:
Do studie bylo zařazeno 9 pacientů s ALI/ARDS.Tlak CPAP během OM byl 50 (49–53) cm H₂O, což vedlo k dosažení Ptrans 24 (20–25) cm H₂O. Během OM došlo ke statisticky významnému poklesu MAP o 33 % (min 7 %, max 61 %) vzhledem hodnotám před OM (p
Závěr:
Transalveolární tlak 30 cm H₂O nebyl během otevíracího manévru dosažen u žadného z pacientů. Během OM nastal signifikantní přechodný pokles MAP, vliv na oxygenaci a ovlivnění splanchnické cirkulace po OM jsme neprokázali.
Klíčová slova:
ARDS – otevírací manévr – hemodynamika – splanchnická cirkulace
Authors:
V. Zvoníček; V. Šrámek
Authors‘ workplace:
Anesteziologicko-resuscitační klinika, Lékařská fakulta Masarykovy univerzity
a Fakultní nemocnice u sv. Anny v Brně
Published in:
Anest. intenziv. Med., 17, 2006, č. 4, s. 208-212
Category:
Intensive Care Medicine - Original Paper
Overview
Objective:
To perform the recruitment manoeuvre (RM) in ARDS patients according to transalveolar pressure (Ptrans = airway pressure minus oesophageal pressure) and to evaluate its impact on gas exchange and the global and splanchnic haemodynamics.
Design:
Prospective, interventional study.
Setting:
Department of Anaesthesia & Intensive Care, St. Anna University Hospital, Brno, Czech Republic.
Methods:
Patients in the early phase of ARDS were enrolled in the study. RM was performed in the CPAP mode for 40 seconds; the aim was to reach transalveolar pressure (Ptrans) of 30 cm H₂O measured by a special bedside respiratory monitoring system.The haemodynamics and blood gases from the pulmonary, radial and hepatic arteries were measured 2 minutes before (preOM), and 2 and 30 minutes after the RM (OM2, OM30). Friedman ANOVA was used for statistical analysis. The data are presented as median and interquartile range.
Results:
Nine ARDS patients were included. During the RM, CPAP of 50 (49–53) and 24 (20–25) cm H₂O was used. Ptrans was reached. MAP decreased by 33% (7–61%) during the RM (P
Conclusion:
During the RM the transalveolar pressure of 30 cm H₂O was not reached in any patient. The RM caused a temporary but significant MAP decrease and did not change oxygenation or the splanchnic circulation.
Key words:
ARDS – recruitment manoeuvre – haemodynamics – splanchnic circulation
Labels
Anaesthesiology, Resuscitation and Inten Intensive Care MedicineArticle was published in
Anaesthesiology and Intensive Care Medicine
2006 Issue 4
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